Friday, April 26, 2013

Intermittent fasting may help those with diabetes and cardiovascular disease, study suggests

Apr. 26, 2013 ? Intermittent fasting is all the rage, but scientific evidence showing how such regimes affect human health is not always clear cut. Now a scientific review in the British Journal of Diabetes and Vascular Disease published by SAGE, suggests that fasting diets may help those with diabetes and cardiovascular disease, alongside established weight loss claims.

Intermittent fasting -fasting on a given number of consecutive or alternate days -- has recently been hailed as a path to weight loss and improved cardiovascular risk. A team led by James Brown from Aston University has evaluated the various approaches to intermittent fasting in the scientific literature. They searched specifically for advantages and limitations in treating obesity and type 2 diabetes using fasting diets.

The basic format of intermittent fasting is to alternate days eating 'normally' with days when calorie consumption is restricted. This can either be done on alternative days, or where two days each week are classed as 'fasting days'. These types of intermittent fasting have been shown in trials to be as effective as or more effective than counting calories every day to lose weight. Evidence from clinical trials shows that fasting can limit inflammation, improve levels of sugars and fats in circulation, and reduce blood pressure. Our fasting bodies change how they select which fuel to burn, improving metabolism and reducing oxidative stress.

For people with obesity, only one drug (orlistat) is currently available in the UK, and gastric surgery is a relatively rare and expensive alternative. Dietary changes remain the most common intervention used for obese people. Fasting is known to help, but former treatments were based on intermittent starving. Today's intermittent fasting regimes are easier to stick to, and are proven to help remove excess pounds melt away.

Scientists have known since the 1940s that intermittent fasting helps us lose weight, and can cut the incidence of diabetes in lab animals. Recent studies have also confirmed that restricting calorie intake could possibly reverse type 2 diabetes in some people. Researchers measured improved pancreatic function and fewer of the fatty deposits associated with insulin resistance were present in fasting subjects.

A healthy heart

In animal models, scientists have shown that intermittent fasting has some cardiovascular benefits that appear similar to exercising, such as improving blood pressure and heart rate, and lowering cholesterol. Fasting also appears to aid those with ischemic heart disease. Fasting may even protect the heart by raising levels of adiponectin, a protein that has several important roles in carbohydrate and lipid metabolism and vascular biology.

"Intermittent fasting might achieve much of the benefit seen with bariatric surgery, but without the costs, restriction on numbers and risks associated with surgery," according to lead author, James Brown. "Whether intermittent fasting can be used as a tool to prevent diabetes in those individuals at high risk or to prevent progression in those recently diagnosed with type 2 diabetes remains a tantalising notion and we are currently in preparation for clinical trials to assess the effectiveness of this form of lifestyle intervention in various patient groups."

Intermittent fasting is an increasingly popular diet plan that hit the headlines in the run up to Christmas 2012 after the release of a book on the subject. Proponents claim that in addition to weight loss, the diet can lead to longer life, and protection against disease, particularly conditions such as dementia and Alzheimer's disease.

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The above story is reprinted from materials provided by SAGE Publications, via EurekAlert!, a service of AAAS.

Note: Materials may be edited for content and length. For further information, please contact the source cited above.


Journal Reference:

  1. James E. Brown, Michael Mosley and Sarah Aldred. Intermittent fasting: a dietary intervention for prevention of diabetes and cardiovascular disease? British Journal of Diabetes and Vascular Disease, April 2013

Note: If no author is given, the source is cited instead.

Disclaimer: This article is not intended to provide medical advice, diagnosis or treatment. Views expressed here do not necessarily reflect those of ScienceDaily or its staff.

Source: http://feeds.sciencedaily.com/~r/sciencedaily/living_well/~3/D78Xbo49i8U/130426115456.htm

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Tuesday, April 23, 2013

9 Materials That Will Change the Future of Manufacturing [Slide Show]

Researchers are developing cutting-edge foams, coatings, metals and other substances to make our homes, vehicles and gadgets more energy efficient and environmentally friendly


manufacturing,materialCHITIN + SILK: Materials have a tremendous influence on the properties of manufactured goods, including weight, strength and energy consumption. The "Shrilk" pictured here was inspired insect exoskeleton material and could someday be used to make biomedical products. Image: Courtesy of Wyss Institute, Harvard University

The future of manufacturing depends on a number of technological breakthroughs in robotics, sensors and high-performance computing, to name a few. But nothing will impact how things are made, and what they are capable of, more than the materials manufacturers use to make those things. New materials change both the manufacturing process and the end result.

Scientific American?s May special report ?How to Make the Next Big Thing? presents several new materials under development to help inventors and engineers deliver next-generation technologies. These ingredients include superinsulating aerogels for spacesuits, flexible concrete cloth for construction projects and complex natural polymers that could replace toxic plastics.

Yet this lineup of advanced materials merely scratches the surface. Carmakers, for example, are developing porous polymers and new steel alloys that are stronger and lighter than steel, ostensibly making vehicles both safer and more fuel efficient. And environmentally savvy entrepreneurs are growing fungi-based packing materials to provide a biodegradable alternative to Styrofoam.

The following slide show presents these and several other substances that manufacturers could someday us to make many of the things we use.

View a slide show of these cutting-edge materials.

Source: http://rss.sciam.com/click.phdo?i=6ea14ea9b9c8bd1a07b58af2a3d9f61a

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Monday, April 22, 2013

Grape intake may protect against metabolic syndrome-related organ damage

Grape intake may protect against metabolic syndrome-related organ damage [ Back to EurekAlert! ] Public release date: 22-Apr-2013
[ | E-mail | Share Share ]

Contact: Justin Harris
juaha@umich.edu
734-764-2220
University of Michigan Health System

Study shows grapes reduced inflammation and fat storage, improved antioxidant defense

ANN ARBOR, MI - Consuming grapes may help protect against organ damage associated with the progression of metabolic syndrome, according to research presented Monday at the Experimental Biology conference in Boston. Natural components found in grapes, known as polyphenols, are thought to be responsible for these beneficial effects.

The study, led by investigator E. Mitchell Seymour, Ph.D., of the University of Michigan Health System, studied the effects of a high fat, American-style diet both with added grapes and without grapes (the control diet) on the heart, liver, kidneys, and fat tissue in obesity-prone rats. The grapes a blend of red, green and black varieties were provided as a freeze-dried grape powder and integrated into the animals' diets for 90 days.

Specifically, the results showed that three months of a grape-enriched diet significantly reduced inflammatory markers throughout the body, but most significantly in the liver and in abdominal fat tissue. Consuming grapes also reduced liver, kidney and abdominal fat weight, compared with those consuming the control diet. Additionally, grape intake increased markers of antioxidant defense, particularly in the liver and kidneys.

Metabolic syndrome is a cluster of conditions that occur together increased blood pressure, a high blood sugar level, excess body fat around the waist or low HDL (the good cholesterol) and increased blood triglycerides significantly increasing the risk for heart disease, stroke and Type 2 diabetes. Intake of fruits and vegetables is thought to reduce these risks, and grapes have shown benefits in multiple studies. Metabolic syndrome is a major public health concern, and is on the rise in the U.S.

"Our study suggests that a grape-enriched diet may play a critical role in protecting against metabolic syndrome and the toll it takes on the body and its organs," said Seymour. "Both inflammation and oxidative stress play a role in cardiovascular disease progression and organ dysfunction in Type 2 diabetes. Grape intake impacted both of these components in several tissues which is a very promising finding."

This work extends and reinforces the findings of Seymour's previously published research which demonstrated that a grape-enriched diet reduced risk factors for heart disease and diabetes in obesity-prone rats.

###

Experimental Biology is a multidisciplinary, scientific meeting focused on research and life sciences, covering general fields of study such as anatomy, biochemistry, nutrition, pathology and pharmacology. The meeting is comprised of nearly 14,000 scientists and exhibitors.


[ Back to EurekAlert! ] [ | E-mail | Share Share ]

?


AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert! system.


Grape intake may protect against metabolic syndrome-related organ damage [ Back to EurekAlert! ] Public release date: 22-Apr-2013
[ | E-mail | Share Share ]

Contact: Justin Harris
juaha@umich.edu
734-764-2220
University of Michigan Health System

Study shows grapes reduced inflammation and fat storage, improved antioxidant defense

ANN ARBOR, MI - Consuming grapes may help protect against organ damage associated with the progression of metabolic syndrome, according to research presented Monday at the Experimental Biology conference in Boston. Natural components found in grapes, known as polyphenols, are thought to be responsible for these beneficial effects.

The study, led by investigator E. Mitchell Seymour, Ph.D., of the University of Michigan Health System, studied the effects of a high fat, American-style diet both with added grapes and without grapes (the control diet) on the heart, liver, kidneys, and fat tissue in obesity-prone rats. The grapes a blend of red, green and black varieties were provided as a freeze-dried grape powder and integrated into the animals' diets for 90 days.

Specifically, the results showed that three months of a grape-enriched diet significantly reduced inflammatory markers throughout the body, but most significantly in the liver and in abdominal fat tissue. Consuming grapes also reduced liver, kidney and abdominal fat weight, compared with those consuming the control diet. Additionally, grape intake increased markers of antioxidant defense, particularly in the liver and kidneys.

Metabolic syndrome is a cluster of conditions that occur together increased blood pressure, a high blood sugar level, excess body fat around the waist or low HDL (the good cholesterol) and increased blood triglycerides significantly increasing the risk for heart disease, stroke and Type 2 diabetes. Intake of fruits and vegetables is thought to reduce these risks, and grapes have shown benefits in multiple studies. Metabolic syndrome is a major public health concern, and is on the rise in the U.S.

"Our study suggests that a grape-enriched diet may play a critical role in protecting against metabolic syndrome and the toll it takes on the body and its organs," said Seymour. "Both inflammation and oxidative stress play a role in cardiovascular disease progression and organ dysfunction in Type 2 diabetes. Grape intake impacted both of these components in several tissues which is a very promising finding."

This work extends and reinforces the findings of Seymour's previously published research which demonstrated that a grape-enriched diet reduced risk factors for heart disease and diabetes in obesity-prone rats.

###

Experimental Biology is a multidisciplinary, scientific meeting focused on research and life sciences, covering general fields of study such as anatomy, biochemistry, nutrition, pathology and pharmacology. The meeting is comprised of nearly 14,000 scientists and exhibitors.


[ Back to EurekAlert! ] [ | E-mail | Share Share ]

?


AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert! system.


Source: http://www.eurekalert.org/pub_releases/2013-04/uomh-gi042213.php

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Wednesday, April 17, 2013

Samsung Galaxy S 4 priced at $150 on Sprint and T-Mobile, hits both carriers in late April

Samsung Galaxy S 4 priced at $150 on Sprint and T-Mobile, hits both carriers in late April

US launch details for the Galaxy S 4 are arriving at last, and both Sprint and T-Mobile are on the vanguard. The two carriers plan to sell Samsung's flagship for $150 in 16GB form, albeit with different pricing strategies: T-Mobile's plan includes its now-standard device payment installments, while Sprint is discounting the phone from its normal $250 price through a $100 instant credit for those switching to the network. Just when you'll have the chance to plunk money down also varies. Sprint plans to offer pre-orders starting on April 18th, with an actual launch on April 27th. T-Mobile isn't giving customers the same opportunity to buy in advance, although they will get to take the Galaxy S 4 home a few days earlier, on April 24th. We're still waiting on other American carriers to hop on the bandwagon, but we suspect it won't be long.

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Source: Sprint, T-Mobile

Source: http://www.engadget.com/2013/04/17/samsung-galaxy-s-4-to-cost-150-at-both-t-mobile-and-sprint/

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Friday, April 5, 2013

University of Miami athletes depend on former Staten Islander Vinny Scavo

The first one to notice was Tammy Scavo.

It was the night before the University of Miami?s Sept. 22 football game at Georgia Tech, and the Hurricanes? head athletic trainer, Vinny Scavo, and his wife of 22 years were sitting in the hotel lobby as a film camera lurked nearby.

?She says, ?What?s that camera doing following you??? the former New Dorp HS pitcher said. ?I said, ?I don?t know.? So I asked around.?

It turned out the camera, at the direction of filmmaker Madison Murr of 3Pennyfilms, was recording Scavo for its next installment of ?Raising Canes,? an internet series shown on Youtube.com and Hurricanes.com which has become a vital part of the Hurricanes? recruiting program. This particular episode dealt with the return of junior defensive end Shayon Green from an ACL injury.

As an instrumental part of Green?s rehab as Miami?s director of athletic training, Scavo was tabbed to make his computer-screen debut after 30 years of taping, flexing and fixing athletes in various organizations. Green had given Murr the go-ahead to film Scavo applying the layers of Hurricane-colored green and orange athletic tape from mid-shin through thigh in the otherwise private confines of the training room.

Scavo, whose sister Maryanne still lives in their childhood home in Grant City, was called on to offer his version of the Green?s rehab and recovery, sanitized of course.

?I said, ?This is beautiful,?? the 52-year-old said. ?I had no idea that was going to happen. I usually drop a few F-bombs in there, but I didn?t do that, or my wife and sister would have yelled at me.

?But it wasn?t uncomfortable. I just went about my business. I didn?t think about it. We usually don?t allow press in there to protect the privacy of our players, but Shayon agreed to do it.? ?

LOTS OF ENTHUSIASM? ?

Scavo?s enthusiasm for his job and his school show through loud and clear on film.

?He was a good sport,? Murr said. ?The trust factor was there. We wanted to get his own story. He said, ?Whatever you need.? He was a great interview. He?s been there so long and is very passionate about the program, so that was a great positive.?

It wasn?t as if Scavo carved out a section of schedule for some face-time. He doesn?t have many leisurely minutes in Coral Gables. Since becoming director of the school?s entire athletic training program last year after head football coach Al Golden hired him to be the his team?s head trainer in 2010, Scavo has overseen the treatment and rehabilitation of the university?s 400 athletes.

As if that hasn?t kept him busy enough, he also tends to U of M alumni who live in the area such as the Baltimore Ravens safety Ed Reed and New Orleans Saints tight end Jimmy Graham, and one former local baseball player of note.

The one who name adorns the school?s baseball stadium.

?We?ve had Alex Rodriguez in here,? Scavo said. ?Our doctor (Dr. Lee Kaplan) operated on him and we?ve had him in. He?s talked to me about different ideas he?s had for his rehab. I have no idea whether he used them or not, but he worked very hard in our strength rooms down the hall.

?He was very nice, very pleasant. To me, he?s just A-Rod, and he needs rehab.?

Scavo has provided those services to every level of athlete since he graduated New Dorp in 1977 after four years playing baseball, his true love, and one playing football. After a semester at St. Francis College in Brooklyn, he ventured south to pitch at Gulf Coast Community College in Panama City, Fla. There, he became interested in athletic training.

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A meeting with future Yankees manager Dick Howser led to temporary stops at Florida State, where Howser was the baseball coach, and the minor league Oneonta Yankees once Howser accepted the Yankees job. Then it was back to college and ?The U,? for stints as assistant football trainer under national championship winners Howard Schnellenberger and Jimmy Johnson.

Upon marrying Tammy in 1991, he took a job at Coral Gables HS that paid more money.

?Believe it or not, I couldn?t afford to be a college trainer,? he said.

The downward step proved no impediment to his being named to the Olympic Trials staff. After that, he directed the minor league training operations for the upstart Florida Marlins from 1992-96. Then it was back to high school until, in 2006, Dr. Kaplan asked him to direct the sports medicine clinic he set up at the University of Miami Hospital. ?

EYE FOR TALENT? ?

He moved on-campus in 2011 when Golden pushed through the construction of a facility dedicated solely to strength, conditioning, and athletic training.

Despite his nearly year-round residence in Florida, Scavo said he remains a Staten Islander at heart. What little vacation time he gets is spent up here, visiting family and old friends and teammates. He bled, right along with his Island brethren, when Superstorm Sandy struck.

?I have (FOX) Five on my satellite and I watch it every night,? Scavo said. ?I told my sister what was happening before she even knew it.?

He also reads The Advance every day to keep up on hometown news. That?s where he learned about Augustus Edwards, Tottenville?s 6-foot-1, 230-pound running back with 4.5 speed. Golden?s staff hadn?t even looked at Edwards until Scavo brought his name up.

A discussion with the school?s recruiting coordinator led to a visit not long ago.

?I met him coming out of the hotel, and he had a Yankees hat on,? Scavo said. ?I said, ?Good move. Good move.??

Edwards committed to the Hurricanes in early February.

If Scavo has his way, Edwards won?t be the last recruit from his old borough.

?We need more Staten Island kids down here,? he said. ?

Source: http://www.silive.com/colleges/index.ssf/2013/04/university_of_miami_athletes_d.html

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